31.
Statins are very effective against hypercholesterolemia, a major cause of atherosclerosis. These drugs reduce plasma cholesterol levels by
A:
Preventing absorption of cholesterol from the intestine.
B:
Increasing the excretion of cholesterol from the body via conversion to bile acids.
C:
Inhibiting the conversion of 3-hydroxy-3-methylglutaryl-CoA to mevalonate in the pathway for cholesterol biosynthesis.
D:
Increasing the rate of degradation of 3-hydroxy-3-methylglutaryl CoA reductase.
The answer is:
C
