A 30-year-old woman of Northern European ancestry presents with progressive dyspnea (shortness of breath). She denies the use of cigarettes. Family history reveals that her sister also has problems with her lungs. Which of the following etiologist most likely explain the patients’ symptoms?

M.Sc. Bio-Chemistry (PU-CET P.G) 2022 Panjab University Entrance Exam With Answers

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A: Deficiency in dietary Vitamin C

B: Deficiency of prolyl hydroxylase

C: Increased collagenase activity

D: Deficiency of α1-antitrypsin

The answer is: D

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