Explanation
The correct word to fill in the blank is B: Of.
The complete sentence is "A prudent person avails himself of opportunities." In this sentence, the word "avails" means to take advantage of or benefit from something. The phrase "of opportunities" is a prepositional phrase that describes what the prudent person is availing themselves of.
The word "of" is the correct preposition to use in this context, as it indicates that the prudent person is taking advantage of something that exists or is available to them.
Option A, "with," would not be appropriate in this context because it implies a sense of cooperation or collaboration with the opportunities, which is not accurate. Option C, "for," would also not be appropriate because it implies that the opportunities are being created for the prudent person, which is not necessarily the case. Option D, "to," would be grammatically correct, but it would change the meaning of the sentence slightly to indicate that the prudent person is seeking out opportunities rather than taking advantage of ones that already exist.
Therefore, the correct preposition to use in this sentence is "of," making the complete sentence "A prudent person avails himself of opportunities."